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The current systematic review and meta-analysis of randomized controlled clinical trials (RCTs) were performed to assess the effect of l-carnitine supplementation on serum levels of enzymes mainly produced by liver [alanine aminotransferase (ALT), aspartate aminotransferase (AST), and gamma-glutamyl transpeptidase (GGTP)]

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Another suggests that a combination of smoking and alcohol can decrease glutathione activity (17)

doi: 10.7554/eLife.83069.sa2 36 CoryellPRDiekmanBOLoeserRF